Sex, AGility, and the Regulation of Alternative Splicing
نویسنده
چکیده
Alternative splicing is an important means of regulating the expression of eukaryotic genes and enhancing protein diversity. A detailed examination of the Drosophila Sex-lethal gene has led to two significant discoveries-the role of the splicing factor SPF45 in defining the site of exon ligation, and that alternative splicing can be regulated at the second step.
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عنوان ژورنال:
- Cell
دوره 109 شماره
صفحات -
تاریخ انتشار 2002